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AQA GCSE Biology — Cells and Organisation flashcards

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Topics 4.1 and 4.2 of AQA GCSE Biology: cell structure, microscopy and culturing, cell division and stem cells, transport in cells, enzymes and digestion, heart and blood, non-communicable disease and plant tissues. Higher Tier and Biology-only cards are marked.

Learn deck · part of AQA GCSE Biology · written against: AQA GCSE Biology (8461) specification, version 1.0; Higher Tier and separate-science-only cards marked on the front. Updated 2026-10-10.

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  1. A cell has a cell membrane, cytoplasm and a cell wall, and its DNA is a single loop lying free in the cytoplasm. Is it eukaryotic or prokaryotic?
    Prokaryotic — it is a bacterial cell.

    Why: its DNA is not held inside a nucleus; plant and animal (eukaryotic) cells keep their DNA inside a nucleus.
    Cell Biology › Cell Structure
  2. What are plasmids, and in which type of cell are they found?
    Small rings of DNA found in bacterial (prokaryotic) cells, separate from the main DNA loop.

    Example: genetic engineers use plasmids as vectors to carry a gene into a bacterium.
    Cell Biology › Cell Structure
  3. A typical animal cell is about 20 µm across and a typical bacterium about 2 µm. By how many orders of magnitude do they differ?
    One order of magnitude — the animal cell is about ten times wider.

    Why: 20 µm ÷ 2 µm = 10, which is 10110^1⁠; each order of magnitude is a factor of ten.
    Cell Biology › Cell Structure
  4. Which sub-cellular structure is the site of aerobic respiration?
    Mitochondria.

    Why: cells that need a lot of energy, such as muscle cells and sperm cells, contain large numbers of them.
    Cell Biology › Cell Structure
  5. Which sub-cellular structure is the site of protein synthesis, and is it found in both eukaryotic and prokaryotic cells?
    Ribosomes — and yes, they are found in both.

    Why: almost every cell must make proteins, including enzymes, so ribosomes occur in plant, animal and bacterial cells alike.
    Cell Biology › Cell Structure
  6. What is the difference between a tissue and an organ?
    A tissue is a set of cells of similar structure sharing a function; an organ is several tissues that work together on particular functions.

    Example: muscle tissue is one of the tissues that make up the stomach.
    Organisation › Principles of Organisation
  7. What is an enzyme?
    A biological catalyst: a large protein molecule that speeds up a reaction without being used up.

    Why: enzymes let the reactions of metabolism happen fast enough at body temperature.
    Organisation › Animal Tissues and Organs
  8. Why does each enzyme catalyse only one specific reaction?
    Its active site has a unique shape that only one substrate fits — the lock and key model.

    Watch out: the substrate is complementary to the active site, not the same shape.
    Organisation › Animal Tissues and Organs
  9. What happens to an enzyme's activity above its optimum temperature, and why?
    The rate falls because the enzyme is denatured: its active site changes shape, so the substrate no longer fits.

    Watch out: an enzyme is not killed; it is a protein, not a living thing.
    Organisation › Animal Tissues and Organs
  10. A protease from the stomach works best at pH 2. Why does it work very slowly at pH 8?
    At pH 8 the active site changes shape (the enzyme is denatured), so the substrate no longer fits.

    Why: each enzyme has an optimum pH at which its active site has exactly the right shape.
    Organisation › Animal Tissues and Organs

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Review status: Second-reader reviewed, with corrections applied.

Checked against:

  • Topic outline follows the AQA GCSE Biology (8461) specification, version 1.0 (outline only; no specification text reproduced).
  • OpenStax Biology 2e, consulted as a reference; no text copied.

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