Pharmacy — Practice Questions: PTCB & Top Drugs flashcards

6 of 70 questions free to study here · 24 topics · the whole deck is built into Willys

Multiple-choice practice questions, one best answer each, on sig codes, federal pharmacy law and safety, storage, top-drug brand and generic names and classes, key interactions and counseling.

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Practice deck · part of PTCB PTCE / NAPLEX · written against: Top-drug lists and federal pharmacy law as of 2026; PTCE content outline effective 6 January 2026. Updated 2026-10-10.

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A new patient's medication list includes Crestor. Which generic drug is this?

A) atorvastatin
B) rosuvastatin
C) pitavastatin
D) pravastatin

B) rosuvastatin

Crestor is rosuvastatin, an HMG-CoA reductase inhibitor (statin) and, with atorvastatin, one of the two statins used for high-intensity LDL lowering. Atorvastatin, the most tempting choice, is Lipitor.
Lipids
A patient taking Zanaflex for muscle spasm is prescribed an antibiotic for a urinary tract infection. Which antibiotic is contraindicated with it?

A) cephalexin
B) ciprofloxacin
C) amoxicillin
D) nitrofurantoin

B) ciprofloxacin

Zanaflex is tizanidine, and ciprofloxacin inhibits CYP1A2, sharply raising tizanidine levels and causing severe hypotension and sedation. Fluvoxamine is the other classic contraindicated partner.
Pain · Muscle & Gout
A patient taking phenelzine asks for an OTC pseudoephedrine decongestant. What is the risk?

A) QT prolongation
B) Severe hypoglycemia
C) A hypertensive crisis
D) Serotonin syndrome

C) A hypertensive crisis

Sympathomimetic decongestants with an MAOI can trigger a hypertensive crisis, so the patient should not take it and is referred for a safer option such as saline spray. Serotonin syndrome is the classic risk with dextromethorphan or meperidine instead.
Serotonergic & MAOI Interactions
An order writes the abbreviation U after a number. Why must U never be used for units?

A) It can be misread as a zero, a 4 or cc
B) It refers only to international units
C) It is reserved for urine volumes
D) It is not accepted by billing systems

A) It can be misread as a zero, a 4 or cc

A handwritten U can be read as a zero, a 4 or cc, causing tenfold or larger overdoses, so unit is written in full. IU is also banned because it can be misread as IV or 10.
Error-Prone Abbreviations
A technician prepares IV admixtures in a cleanroom. Which USP chapter sets the standards for this work?

A) USP chapter 797
B) USP chapter 795
C) USP chapter 825
D) USP chapter 800

A) USP chapter 797

Chapter 797 covers sterile compounding, including cleanroom, garbing and beyond-use dating standards. Chapter 795 covers nonsterile preparations such as creams and oral suspensions.
Compounding Standards
A shipment of unopened insulin pens arrives. Within which USP range should they be stored?

A) −25 to −10 °C (−13 to 14 °F)
B) 8 to 15 °C (46 to 59 °F)
C) 2 to 8 °C (36 to 46 °F)
D) 20 to 25 °C (68 to 77 °F)

C) 2 to 8 °C (36 to 46 °F)

Refrigerated storage is 2 to 8 °C, used for most unopened insulin and many vaccines. Insulin must never be frozen, so the −25 to −10 °C freezer range is wrong.
Storage

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More PTCB PTCE / NAPLEX decks

Top Drugs: Brand ↔ Generic, Part 1 Top Drugs: Brand ↔ Generic, Part 2 Interactions, Adverse Effects & Counseling Cloze: Top Drugs & Counseling PTCB Practice: Sig Codes, Law & Safety Cardiovascular and Renal Endocrine and GI Pulmonary, Oncology and Immunology Infectious Disease CNS, Psychiatry and Pain Practice Questions, Part 1 Practice Questions, Part 2

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About these cards

Review status: Second-reader reviewed, with corrections applied.

Checked against:

Law items checked against the Controlled Substances Act and 21 CFR Part 1300 series and the DEA Pharmacist's Manual, recall classes against 21 CFR 7.3, child-resistant packaging against 16 CFR 1700, privacy against the HIPAA rules (45 CFR Parts 160 and 164) and counseling duties against OBRA '90 (US government; public domain); abbreviation and look-alike items against The Joint Commission Do Not Use list and ISMP's error-prone abbreviation and confused drug name lists; reference only, no text copied.
Recall classes, NDC structure (including FDA's 2026 final rule on the 12-digit format) and Orange Book codes checked against FDA web pages and the Federal Register (public domain); USP chapter scopes and storage definitions against USP General Notices; drug names, classes, interactions and counseling points against FDA prescribing information on DailyMed (US National Library of Medicine; public domain) and the FDA table of CYP substrates, inhibitors and inducers; reference only.

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Not clinical guidance. These cards prepare you for an exam. Never use them to make decisions about a patient's care: follow current guidelines, prescribing information and your institution's policies. The decks contain no doses.

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